Gene information
Official symbol GLP1R
Official full name glucagon like peptide 1 receptor
Gene type protein-coding gene
Chromosome6p21.2
Alias symbolGLP-1R
Gene familyGlucagon receptor family
Resources
Entrez Gene 2740
HGNC HGNC:4324
Ensembl ENSG00000112164
Vega OTTHUMG00000014638
UCSC uc003ooj.5
GO terms: 33 records
GO Description Category LogP Number of genes Detail
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO Biological Processes -6.95524830 22 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0007611 learning or memory GO Biological Processes -7.55755517 33 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008016 regulation of heart contraction GO Biological Processes -27.6827716 55 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009914 hormone transport GO Biological Processes -6.35710158 16 More
GO:0017046 peptide hormone binding GO Molecular Functions -2.85990067 8 More
GO:0019932 second-messenger-mediated signaling GO Biological Processes -19.1717114 46 More
GO:0019935 cyclic-nucleotide-mediated signaling GO Biological Processes -6.37341307 8 More
GO:0023061 signal release GO Biological Processes -5.50151396 21 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0032940 secretion by cell GO Biological Processes -8.42144465 43 More
GO:0033218 amide binding GO Molecular Functions -9.50305686 47 More
GO:0042562 hormone binding GO Molecular Functions -4.16724021 13 More
GO:0043434 response to peptide hormone GO Biological Processes -26.1739008 69 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0045776 negative regulation of blood pressure GO Biological Processes -17.1357953 22 More
GO:0046879 hormone secretion GO Biological Processes -6.27678757 15 More
GO:0046903 secretion GO Biological Processes -18.5147167 70 More
GO:0050890 cognition GO Biological Processes -8.00500082 37 More
GO:0071375 cellular response to peptide hormone stimulus GO Biological Processes -15.9961580 44 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071806 protein transmembrane transport GO Biological Processes -2.00492833 4 More
GO:0140352 export from cell GO Biological Processes -8.94733589 48 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04024 cAMP signaling pathway KEGG Pathway -7.78464854 30 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
Drug-Gene interaction
view
Related drugs: 151 records
Drug name Interaction type Source PMID View
2-methoxyestradiol DTC view
6-azauridine DTC view
albiglutide agonist TdgClinicalTrialChemblInteractionsTTD 25136065 view
albuterol DTC view
amcinafide DTC view
amorfrutin a DTC view
angustibalin DTC view
asterric acid DTC view
aurin DTC view
benzpiperylon DTC view
cetylpyridinium bromide DTC view
chembl1170485 DTC view
chembl1224483 DTC view
chembl1256697 DTC view
chembl1256746 DTC view
chembl1270168 DTC view
chembl127579 DTC view
chembl1308346 DTC view
chembl1327172 DTC view
chembl1337519 DTC view
chembl1390716 DTC view
chembl1420370 DTC view
chembl1422704 DTC view
chembl1437888 DTC view
chembl1439833 DTC view
chembl1466186 DTC view
chembl1472891 DTC view
chembl1509103 DTC view
chembl1520282 DTC view
chembl1543865 DTC view
chembl1549738 DTC view
chembl1569494 DTC view
chembl259615 DTC view
chembl259805 DTC view
chembl260451 DTC view
chembl261693 DTC view
chembl317115 DTC view
chembl405914 DTC view
chembl482050 DTC view
chembl493863 DTC view
chembl524376 DTC view
chembl528181 DTC view
chembl528791 DTC view
chembl530609 DTC view
chembl532412 DTC view
chembl532452 DTC view
chembl533082 DTC view
chembl533602 DTC view
chembl548286 DTC view
chembl576809 DTC view
chembl578515 DTC view
chembl578928 DTC view
chembl579318 DTC view
chembl579956 DTC view
chembl580076 DTC view
chembl580207 DTC view
chembl580340 DTC view
chembl580727 DTC view
chembl581152 DTC view
chembl581865 DTC view
chembl581872 DTC view
chembl582286 DTC view
chembl584269 DTC view
chembl584458 DTC view
chembl585443 DTC view
chembl585444 DTC view
chembl586078 DTC view
chembl586163 DTC view
chembl587564 DTC view
chembl588028 DTC view
chembl588038 DTC view
chembl588683 DTC view
chembl589245 DTC view
chembl589670 DTC view
chembl589909 DTC view
chembl590427 DTC view
chembl590686 DTC view
chembl590919 DTC view
chembl591126 DTC view
chembl591598 DTC view
chembl591834 DTC view
chembl592118 DTC view
chembl597244 DTC view
chembl597251 DTC view
chembl599100 DTC view
chembl600734 DTC view
chembl601351 DTC view
chembl601400 DTC view
chembl602012 DTC view
chembl602923 DTC view
chembl603130 DTC view
chembl603154 DTC view
chembl604321 DTC view
chembl604664 DTC view
chembl605708 DTC view
chembl606460 DTC view
chembl607309 DTC view
chembl86464 DTC view
clanfenur DTC view
clotrimazole DTC view
cloxyquin DTC view
clozapine PharmGKB 24624910 view
colforsin DTC view
coronopilin DTC view
cycloaspeptide a DTC view
cycloheximide DTC view
desipramine hydrochloride DTC view
digitoxigenin DTC view
dihydroxanthohumol DTC view
dulaglutide agonist TdgClinicalTrialChemblInteractionsTTD 25367716 view
duloxetine hydrochloride DTC view
enclomiphene DTC view
etoposide DTC view
exenatide agonist TdgClinicalTrialChemblInteractionsTENDPharmGKBTTD 16627399167228151729297715700891206495951634128811752352308832641549598817353295165345271533155117379930 view
fenbendazole DTC view
fenticlor DTC view
fiduxosin hydrochloride DTC view
gerontoxanthone h DTC view
glp-1 TTD view
helenalin DTC view
homidium bromide DTC view
indoprofen DTC view
kepone DTC view
lasalocid a sodium DTC view
liraglutide agonist TdgClinicalTrialChemblInteractionsPharmGKBTTD 146780211833388925991051 view
lixisenatide agonist ChemblInteractionsTTD view
magnolol DTC view
mepazine acetate DTC view
metaphit methanesulfonate DTC view
mitonafide DTC view
mofebutazone DTC view
nortriptyline hydrochloride DTC view
olanzapine PharmGKB 24624910 view
oxycarboxin DTC view
paroxetine hydrochloride DTC view
pegapamodutide TTD view
pinafide DTC view
pramlintide TTD view
propionylpromazine hydrochloride DTC view
pyrithione DTC view
pyronin y DTC view
pyroxamine maleate DTC view
sar425899 TTD view
scoulerine DTC view
semaglutide agonist ChemblInteractionsTTD 2414009421314233 view
sitagliptin PharmGKB 27160388 view
strophanthidin DTC view
taspoglutide agonist TdgClinicalTrialChemblInteractionsTTD view
triclabendazole DTC view
trifluoperazine DTC view
vildagliptin PharmGKB 27160388 view
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
glucagon-like peptide 1 receptor proteomics ST elevation myocardial infarction[diagnosis] ST elevation myocardial infarction Diebold S et al. Diabetes Obes Metab. 2018
glucagon-like peptide 1 receptor proteomics adverse events[prognosis (bad)] acute myocardial infarction Kahles F et al. Eur Heart J. 2019
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